2010 Paper 9 Question 3
Bioinformatics
(a) Discuss why the use of spaced seeds in sequence database search is better than
the use of consecutive seeds. [5 marks]
(b) Discuss the complexity of Sankoff’s parsimony method. [5 marks]
(c) Describe the four points conditions in phylogeny. [5 marks]
(d) Discuss the assumptions of the Gillespie algorithms. [5 marks]